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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2D
All Species:
18.48
Human Site:
S306
Identified Species:
33.89
UniProt:
Q14814
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14814
NP_005911.1
521
55938
S306
G
V
S
Q
S
T
H
S
L
T
T
P
V
V
S
Chimpanzee
Pan troglodytes
XP_001165500
521
55889
S306
G
V
S
Q
S
T
H
S
L
T
T
P
V
V
S
Rhesus Macaque
Macaca mulatta
XP_001103222
500
53974
P304
S
S
S
Q
A
T
Q
P
L
A
T
P
V
V
S
Dog
Lupus familis
XP_547534
525
56508
L306
P
P
T
H
S
A
Q
L
G
A
P
S
R
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q63943
514
54974
S306
G
V
S
Q
S
T
H
S
L
T
T
P
V
V
S
Rat
Rattus norvegicus
O89038
507
54350
S306
S
L
T
T
P
V
V
S
V
A
T
P
S
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507540
505
54598
Q306
I
S
S
S
Q
S
T
Q
P
L
A
T
P
V
V
Chicken
Gallus gallus
Q9W6U8
499
53650
P308
S
S
S
Q
S
T
Q
P
L
A
T
P
V
V
S
Frog
Xenopus laevis
Q03413
498
54053
S306
G
V
S
Q
A
T
H
S
L
T
T
P
V
V
S
Zebra Danio
Brachydanio rerio
NP_571392
529
57466
T306
Q
V
T
Q
P
L
T
T
P
V
V
S
V
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
S306
G
A
Q
D
F
S
S
S
G
V
M
N
S
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
D88
E
E
D
C
A
E
V
D
I
L
K
D
Q
L
S
Baker's Yeast
Sacchar. cerevisiae
Q12224
676
73465
D306
S
P
S
N
S
L
E
D
S
I
Q
Q
T
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
53.7
72.5
N.A.
96.1
94.4
N.A.
54.1
54.7
73.6
70.1
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
63.9
75.8
N.A.
97.1
95.5
N.A.
64.8
64.3
82.5
78.2
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
6.6
N.A.
100
20
N.A.
13.3
66.6
93.3
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
13.3
N.A.
100
46.6
N.A.
20
66.6
100
40
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
24
8
0
0
0
31
8
0
0
16
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
16
0
0
0
8
0
0
8
% D
% Glu:
8
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
39
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
31
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% K
% Leu:
0
8
0
0
0
16
0
8
47
16
0
0
0
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
16
0
0
16
0
0
16
16
0
8
54
8
0
8
% P
% Gln:
8
0
8
54
8
0
24
8
0
0
8
8
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
31
24
62
8
47
16
8
47
8
0
0
16
16
0
54
% S
% Thr:
0
0
24
8
0
47
16
8
0
31
54
8
8
0
8
% T
% Val:
0
39
0
0
0
8
16
0
8
16
8
0
54
62
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _